Usage guide

This tutorial goes over using memento to compare 2 groups of cells in a scRNA-seq dataset.

This assumes that there are no hierarchical structures in the data, such as different biological/technical replicates.

Simple binary

Two groups of cells and no covariates: Notebook

Binary testing with replicates

Fixed effect binary testing with multiple samples: Notebook

Testing with covariates and between sample variability

eQTL analysis (hierarchical bootstrap): Notebook

Quasi-ML approach (in development)